dc.contributor.authorLiang, Jing
dc.contributor.authorLi, Kai
dc.contributor.authorGurzadyan, Gagik G.
dc.contributor.authorLu, Xianmao
dc.contributor.authorLiu, Bin
dc.date.accessioned2013-07-15T02:14:52Z
dc.date.available2013-07-15T02:14:52Z
dc.date.copyright2012en_US
dc.date.issued2012
dc.identifier.urihttp://hdl.handle.net/10220/11355
dc.description.abstractWe present the study of silver nanocube (Ag NC)-enhanced fluorescence of a cationic conjugated polyelectrolyte (CPE) for far-red/near-infrared fluorescence cell imaging. Layer-by-layer self-assembly of polyelectrolytes on 78 nm Ag NCs is used to control CPE–metal distance and its effect on CPE fluorescence. The highest fluorescence enhancement factor (FEF) is obtained for Ag NCs with two bilayers, corresponding to a CPE–metal spacer thickness of 6 nm. At the optimal excitation wavelength, the FEF is 13.8 with respect to the control silica nanoparticles (NPs). The fluorescent NPs are further used for cellular imaging studies. The CPE-loaded Ag NCs with two bilayers exhibit excellent image contrast, superior to the control of CPE–silica NP at a similar uptake efficiency. The viability test indicates low cytotoxicity of the CPE-loaded Ag NCs, rendering them as promising cell imaging agents.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesLangmuiren_US
dc.rights© 2012 American Chemical Society.en_US
dc.subjectDRNTU::Science::Physics
dc.titleSilver nanocube-enhanced far-red/near-infrared fluorescence of conjugated polyelectrolyte for cellular imagingen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.identifier.doihttp://dx.doi.org/10.1021/la302511e


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