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Title: Recent development of cyclodextrin chiral stationary phases and their applications in chromatography
Authors: Xiao, Yin
Ng, Siu-Choon
Tan, Thatt Yang Timothy
Wang, Yong
Keywords: DRNTU::Engineering::Chemical engineering
Issue Date: 2012
Source: Xiao, Y., Ng, S.-C., Tan, T. Y. T., & Wang, Y. (2012). Recent development of cyclodextrin chiral stationary phases and their applications in chromatography. Journal of chromatography A, 1269, 52-68.
Series/Report no.: Journal of chromatography A
Abstract: The current article reviews the development and applications of novel cyclodextrin chiral stationary phases (CD-CSPs) in liquid chromatography (LC), capillary electrochromatography (CEC), gas chromatography (GC) and supercritical fluid chromatography (SFC) over the period of January 2007 to March 2012. The synthetic routes of CD-CSPs, as well as the presence of selective functional groups in effecting inclusion complexation and molecular interactions have been found to exert profound influence in the enantioseparation process. In this article, various synthetic and functional groups immobilization strategies of novel CD-CSPs, and their applications in chiral resolution using different chromatography techniques are discussed. After introducing the topic in Section 1, Section 2 describes novel CD-CSPs in LC applications, where the CSPs are classified according to its coating approaches (physical and chemical manners) for ease of readership. Section 3 discusses recent development of CD-CSPs in open tubular CEC (OT-CEC), packed-bed CEC (P-CEC), pseudostationary phase CEC (PSP-CEC) and monolithic CEC. The last part illustrates novel CD-CSPs in gas chromatography (GC) and supercritical fluid chromatography (SFC).
ISSN: 0021-9673
DOI: 10.1016/j.chroma.2012.08.049
Rights: © 2012 Elsevier B.V.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SCBE Journal Articles

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