Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/84658
Title: Quantitative diagnosis of cervical precancer using fluorescence intensity and lifetime imaging from the stroma
Authors: Jun, Gu.
Yaw, Fu Chit.
Koon, Ng Beng.
Gulam Razul, Sirajudeen.
Kim, Lim Soo.
Keywords: DRNTU::Engineering::Electrical and electronic engineering
Issue Date: 2012
Source: Jun, G., Yaw, F. C., Koon, N. B., Gulam Razul, S., & Kim, L. S. (2012). Quantitative diagnosis of cervical precancer using fluorescence intensity and lifetime imaging from the stroma . 2012 Photonics Global Conference (PGC).
Abstract: Fluorescence microscopy has been widely used in characterizing the pathological states of tissues because intensity and spectra arise from fluorescence emission can reveal structural and biochemical information of biological samples and the fluorescence excited state lifetime has been verified to identify tissue pathology due to its sensitivity to the fluorophore microenvironment. In this study, we have demonstrated that early cervical cancer can be quantitatively diagnosed using intensity and lifetime derived from the stroma fluorescence in conjunction with extreme learning machine (ELM) classifier which can result in a concurrently high sensitivity of 99.1% and specificity of 99.6%. The results suggest that the proposed technique can be used to aid and supplement the traditional histopathological examination of cervical precancer.
URI: https://hdl.handle.net/10356/84658
http://hdl.handle.net/10220/12170
DOI: 10.1109/PGC.2012.6458087
Rights: © 2012 IEEE.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:EEE Conference Papers

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