Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
Shum, Perry Ping
Date of Issue2012
Plasmonics in Biology and Medicine (9th : 2012 : San Francisco, USA)
School of Electrical and Electronic Engineering
We have analyzed and compared the spectral differential phase sensing performance for conventional and long-range (LR) surface plasmon resonance (SPR) across a wide sample refractive index range (i.e. dynamic range) of 1.3330- 1.3505 using Fresnel's Equations and Transfer Matrix method. We demonstrate that wide-range detection limit as high as 7.9×10-9 RIU (Refractive Index Unit) for conventional SPR can be achieved with a set of optimized sensing parameters and a phase measurement resolution of 2×10-4 rad, whereas best detection limit for LRSPR is lower. We have also investigated for the effect of sensing parameters including angle of incidence, metal film material and thickness. LRSPR is found to be quite tolerant to the choice of material and thickness of metal film. This work presents a comprehensive comparison between conventional and LR SPR for spectral-phase configuration.
DRNTU::Engineering::Electrical and electronic engineering
© 2012 SPIE. This paper was published in Proceedings of SPIE - Plasmonics in Biology and Medicine IX and is made available as an electronic reprint (preprint) with permission of SPIE. The paper can be found at the following official DOI: [http://dx.doi.org/10.1117/12.906756]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.