dc.contributor.authorChin, Lip Ket
dc.contributor.authorLuo, K. Q.
dc.contributor.authorPark, W.
dc.contributor.authorJe, Minkyu
dc.contributor.authorTsai, J.
dc.contributor.authorKwong, Dim Lee
dc.contributor.authorLiu, A. Q.
dc.date.accessioned2013-07-29T07:50:25Z
dc.date.available2013-07-29T07:50:25Z
dc.date.copyright2012en_US
dc.date.issued2012
dc.identifier.citationChin, L. K., Luo, K. Q., Park, W., Je, M., Tsai, J., Kwong, D. L., et al. (2012). Double-layer hepatocyte tumor co-culture using hydrogel for drug effectivity and specificity analysis. 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS).en_US
dc.identifier.urihttp://hdl.handle.net/10220/12493
dc.description.abstractThis paper presents the formation of double-layer cellular tumor spheroid for the co-culture of hepatocyte (HepG2 cancer liver cell and LO2 normal liver cell) using alginate hydrogel. With the microfluidic chip, double-layer cellular tumor spheroid can be formed by the hydrogel droplet to mimic the in vivo environment in which the cancer cell is surrounded by normal cell. A microchip with concentration gradient generation and tumor spheroid trapping site is designed for anti-cancer drug analysis.en_US
dc.language.isoenen_US
dc.rights© 2012 IEEE .en_US
dc.subjectDRNTU::Science::Medicine::Biomedical engineering
dc.titleDouble-layer hepatocyte tumor co-culture using hydrogel for drug effectivity and specificity analysisen_US
dc.typeConference Paper
dc.contributor.conferenceIEEE International Conference on Micro Electro Mechanical Systems (25th : 2012 : Paris, France)en_US
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.contributor.schoolSchool of Electrical and Electronic Engineeringen_US
dc.identifier.doihttp://dx.doi.org/10.1109/MEMSYS.2012.6170309


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