Please use this identifier to cite or link to this item:
Title: Palladium-catalyzed cross-coupling of unactivated alkenes with Acrylates: application to the synthesis of the C13-C21 fragment of Palmerolide A
Authors: Wen, Zhen-Kang
Xu, Yun-He
Loh, Teck-Peng
Issue Date: 2012
Source: Wen, Z. K., Xu, Y. H.,& Loh, T. P. (2012). Palladium-Catalyzed Cross-Coupling of Unactivated Alkenes with Acrylates: Application to the Synthesis of the C13-C21 Fragment of Palmerolide A. Chemistry - A European Journal, 18(42), 13284-13287.
Series/Report no.: Chemistry - a European journal
Abstract: Diene to meet: A palladium-catalyzed cross-coupling reaction between alkyl-substituted olefins and acrylates gives the corresponding butadienes in moderate yield and stereoselectivity. This atom-economical reaction, which forms Cmath image–Cmath image bonds, tolerates a wide range of allylic and homoallylic alcohols, and acrylates (see scheme; TIPS =triisopropylsilyl). The methodology was applied to the synthesis of the C13–C21 fragment of palmerolide A.
ISSN: 0947-6539
DOI: 10.1002/chem.201201806
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.