dc.contributor.authorThong, Patricia Soo-Ping
dc.contributor.authorOlivo, Malini
dc.contributor.authorTandjung, Stephanus Surijadarma
dc.contributor.authorMovania, Muhammad Mobeen
dc.contributor.authorLin, Feng
dc.contributor.authorQian, Kemao
dc.contributor.authorSeah, Hock Soon
dc.contributor.authorSoo, Khee-Chee
dc.description.abstractThe cancer burden is increasing worldwide and there is a need to develop new technologies for cancer diagnosis. Confocal laser endomicroscopy (CLE) is a minimally invasive optical technique that enables in vivo confocal imaging of tissue structures. With the use of fluorescent dyes, the technique allows confocal fluorescence endomicroscopy of tissue from surface to subsurface layers. CLE has been applied to the surveillance and diagnosis of cancer in numerous clinical studies recently, and also holds potential for optical and guided biopsy procedures. The first part of this mini review is focused on the application of CLE for cancer detection and surveillance. The second part is focused on the application of CLE to imaging of the oral cavity. We have previously demonstrated the potential of CLE for diagnostic imaging of oral cavity lesions. To move toward real-time 3-D imaging, we interfaced an endomicroscope to an embedded computing system. The prototype system is capable of automated image acquisition and real-time volume rendering. Rendering results provide topographical and depth information. Our aim is to achieve a real-time 3-D fluorescence imaging system that can be used for diagnostic imaging and guided biopsy procedures of oral cavity lesions in a clinical setting.en_US
dc.relation.ispartofseriesIEEE journal of selected topics in quantum electronicsen_US
dc.rights© 2011 IEEEen_US
dc.subjectDRNTU::Engineering::Computer science and engineering
dc.titleReview of confocal fluorescence endomicroscopy for cancer detectionen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Computer Engineeringen_US

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