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Web-based cognitive bias intervention for psychiatric disorders: protocol for a systematic review
(2018)Background: Traditional psychological therapies focus mainly on modification of individuals’ conscious decision-making process. Unconscious processes, such as cognitive biases, have been found accountable for various ... -
Serum progesterone distribution in normal pregnancies compared to pregnancies complicated by threatened miscarriage from 5 to 13 weeks gestation : a prospective cohort study
(2018)Background: Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the distribution of maternal serum progesterone in normal ... -
The role of PPARβ/δ in melanoma metastasis
(2018)Background: Peroxisome proliferator–activated receptor (PPAR) β/δ, a ligand-activated transcription factor, is involved in diverse biological processes including cell proliferation, cell differentiation, inflammation and ... -
Modeling the origin of the ocular pulse and its impact on the optic nerve head
(2018)Purpose: To use finite element (FE) analysis to understand the origin of the ocular pulse and predict its biomechanical impact on the optic nerve head (ONH). Methods: An FE model of a healthy eye was reconstructed. The ... -
Maternal feeding practices in relation to dietary intakes and BMI in 5 year-olds in a multi-ethnic Asian population
(2018)Background: In Asia, little is known about how maternal feeding practices are associated with dietary intakes and body mass index (BMI) in preschoolers. Objective: To assess the relationships between maternal feeding ... -
Cyclooxygenase-2 selectively controls renal blood flow through a novel pparβ/δ-dependent vasodilator pathway
(2018)Cyclooxygenase-2 (COX-2) is an inducible enzyme expressed in inflammation and cancer targeted by nonsteroidal anti-inflammatory drugs. COX-2 is also expressed constitutively in discreet locations where its inhibition drives ... -
Quality of health literacy instruments used in children and adolescents : a systematic review
(2018)Objective: Improving health literacy at an early age is crucial to personal health and development. Although health literacy in children and adolescents has gained momentum in the past decade, it remains an under-researched ... -
Differences in clinical features and dengue severity between local and migrant Chinese with dengue infection in Singapore
(2018)Dengue is endemic in Singapore but not China. We compared clinical features and disease severity of dengue between local and migrant Chinese, most of whom were construction workers, in Singapore. A retrospective study with ... -
Bacteria display differential growth and adhesion characteristics on human hair shafts
(2018)Apart from the skin surface, hair represents a significant tissue component with a capacity of bacterial interactions. New information can be obtained about hair function through the characterization of bacterial adherence, ... -
TFPI-2 protects against gram-negative bacterial infection
(2018)Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we ... -
Biomarkers of cellular senescence and skin aging
(2018)Cellular senescence is an irreversible growth arrest that occurs as a result of different damaging stimuli, including DNA damage, telomere shortening and dysfunction or oncogenic stress. Senescent cells exert a pleotropic ... -
Systems medicine disease : disease classification and scalability beyond networks and boundary conditions
(2018)In order to accommodate the forthcoming wealth of health and disease related information, from genome to body sensors to population and the environment, the approach to disease description and definition demands re-examination. ... -
The endoderm from a diverse perspective
(2018)The historic town of Taos, New Mexico, with its rich multicultural history of art and craft, was the site of the second Keystone Symposium on ‘Endoderm Development and Disease’, which was held in February 2018. The theme ... -
Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species
(2016)Background: The genus Bordetella consists of nine species that include important respiratory pathogens such as the ‘classical’ species B. bronchiseptica, B. pertussis and B. parapertussis and six more distantly related and ... -
Mobile phone cognitive bias modification research platform for substance use disorders : protocol for a feasibility study
(2018)Background: Cognitive biases refer to automatic attentional and interpretational tendencies, which could be retained by cognitive bias modification interventions. Cristea et al and Jones et al have published reviews (in ... -
Internet-based interventions for smoking cessation
(2017)Background: Tobacco use is estimated to kill 7 million people a year. Nicotine is highly addictive, but surveys indicate that almost 70% of US and UK smokers would like to stop smoking. Although many smokers attempt to ... -
No association between resistance mutations, empiric antibiotic, and mortality in ceftriaxone-resistant Escherichia coli and Klebsiella pneumoniae bacteremia
(2018)The objective of this study was to correlate resistance mutations of extended spectrum beta-lactamases (ESBL) and AmpC beta-lactamases and virulence factors (VF) with 30-day mortality in patients treated with either ... -
A novel method for segmenting growth of cells in sheared endothelial culture reveals the secretion of an anti-inflammatory mediator
(2018)Background: Effects of shear stress on endothelium are important for the normal physiology of blood vessels and are implicated in the pathogenesis of atherosclerosis. They have been extensively studied in vitro. In one ... -
The role of eLearning in health management and leadership capacity building in health system : a systematic review
(2018)Background: Health leadership and management are essential for ensuring resilient health systems. Relevant training opportunities are often scarce, and the use of digital education could help address this gap. Our aim was ... -
Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
(2018)Chromosomal instability (CIN), a high rate of chromosome loss or gain, is often associated with poor prognosis and drug resistance in cancers. Aneuploid, including near-polyploid, cells contain an abnormal number of ...
