Synthesis of block copolymers of varying architecture through suppression of transesterification during coordinated anionic ring opening polymerization
Lipik, Vitali T.
Abadie, Marc J. M.
Date of Issue2012
School of Materials Science and Engineering
Well-defined di- and triblock copolymers consisting of ε-caprolactone (CL), L-lactide (LA), and trimethylene carbonate (TMC) were synthesized via “PLA first route” in coordinated anionic ring opening polymerization/copolymerization (CAROP) with tin (II) octoate as catalyst. The desired block structure was preserved by use of protective additive α-methylstyrene by preventing the transesterification side-reactions. MALDI-TOF analysis revealed that the protection mechanism is associated with α-methylstyrene and tin (II) octoate complexation. Additionally, it was shown that use of α-methylstyrene in ring opening polymerization allowed the formation of polyesters with high molar mass.
International journal of biomaterials
© 2012 The Authors. This paper was published in International journal of biomaterials and is made available as an electronic reprint (preprint) with permission of the authors. The paper can be found at the following official DOI: [http://dx.doi.org/10.1155/2012/390947]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.