dc.contributor.authorPetersen, Mette T.
dc.contributor.authorNielsen, Thomas E.
dc.date.accessioned2013-11-19T04:00:21Z
dc.date.available2013-11-19T04:00:21Z
dc.date.copyright2013en_US
dc.date.issued2013
dc.identifier.citationPetersen, M. T., & Nielsen, T. E. (2013). Tandem Ring-Closing Metathesis/Isomerization Reactions for the Total Synthesis of Violacein. Organic Letters, 15(8), 1986-1989.en_US
dc.identifier.urihttp://hdl.handle.net/10220/17769
dc.description.abstractA series of 5-substituted 2-pyrrolidinones was synthesized through a one-pot ruthenium alkylidene-catalyzed tandem RCM/isomerization/nucleophilic addition sequence. The intermediates resulting from RCM/isomerization showed reactivity toward electrophiles in aldol condensation reactions which provided a new entry for the total synthesis of the antileukemic natural product violacein.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesOrganic lettersen_US
dc.subjectDRNTU::Science::Biological sciences
dc.titleTandem ring-closing metathesis/isomerization reactions for the total synthesis of violaceinen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.identifier.doihttp://dx.doi.org/10.1021/ol400654r


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