dc.contributor.authorTeo, Soo-Kng
dc.contributor.authorYang, Yuxin
dc.contributor.authorReeth, Eric Van
dc.contributor.authorHe, Shuai
dc.contributor.authorChua, Peijun
dc.contributor.authorPoh, Chueh Loo
dc.date.accessioned2013-12-04T04:59:37Z
dc.date.available2013-12-04T04:59:37Z
dc.date.copyright2013en_US
dc.date.issued2013
dc.identifier.citationTeo, S.-K., Yang, Y., Reeth, E. V., He, S., Chua, P., & Poh, C. L. (2013). Tracking of tumor motion in lung cancer using patient specific finite element modeling and 4D-MRI image data. Biomedical engineering.en_US
dc.identifier.urihttp://hdl.handle.net/10220/18026
dc.description.abstractThis paper presents a study that demonstrates the potential of using finite element (FE) lung model constructed using 4D-MRI (3D + time) for tracking tumor motion during a respiratory cycle. A series of volumetric images of one lung cancer patient was acquired over time under free breathing and sorted into respiratory phases. A FE model of the lung with the tumor was constructed using the volume which is at full exhale phase. Displacement field from this initial volume to the subsequent 3D volumes in the respiratory phases were derived using a deformable image registration technique. This displacement field which provides displacement information of the lung surface is then used to predict the tumor motion in the lung interior using the FE model. Our results showed that the tumor motion (as represented by the trajectory of the tumor centroid) follows a highly non-linear path during the respiratory cycle from the full exhale phase to the full inhale phase. We also showed that the predicted tumor motion from our FE model is in reasonable agreement with that computed from 4D-MRI.en_US
dc.language.isoenen_US
dc.subjectDRNTU::Engineering::Chemical engineering::Biochemical engineering
dc.titleTracking of tumor motion in lung cancer using patient specific finite element modeling and 4D-MRI image dataen_US
dc.typeConference Paper
dc.contributor.conferenceBiomedical Engineeringen_US
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.identifier.doihttp://dx.doi.org/10.2316/P.2013.791-153


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