dc.contributor.authorZeng, Jing
dc.contributor.authorTan, Yu Jia
dc.contributor.authorMa, Jimei
dc.contributor.authorLeow, Min Li
dc.contributor.authorTirtorahardjo, Davin
dc.contributor.authorLiu, Xue-Wei
dc.date.accessioned2014-03-27T05:32:50Z
dc.date.available2014-03-27T05:32:50Z
dc.date.copyright2014en_US
dc.date.issued2014
dc.identifier.citationZeng, J., Tan, Y. J., Ma, J., Leow, M. L., Tirtorahardjo, D., & Liu, X.-W. (2014). Facile access to cis-2,6-disubstituted tetrahydropyrans by palladium-catalyzed decarboxylative allylation : total syntheses of (±)-centrolobine and (+)-decytospolides A and B. Chemistry - A European Journal, 20(2), 405-409.en_US
dc.identifier.issn0947-6539en_US
dc.identifier.urihttp://hdl.handle.net/10220/18986
dc.description.abstractcis-2,6-Tetrahydropyran is an important structural skeleton of bioactive natural products. A facile synthesis of cis-2,6-disubstituted-3,6-dihydropyrans as cis-2,6-tetrahydropyran precursors has been achieved in high regio- and stereoselectivity with high yields. This reaction involves a palladium-catalyzed decarboxylative allylation of various 3,4-dihydro-2H-pyran substrates. Extending this reaction to 1,2-unsaturated carbohydrates allowed the achievement of challenging β-C-glycosylation. Based on this methodology, the total syntheses of (±)-centrolobine and (+)-decytospolides A and B were achieved in concise steps and overall high yields.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesChemistry - a European journalen_US
dc.rights© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.en_US
dc.subjectDRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
dc.titleFacile access to cis-2,6-disubstituted tetrahydropyrans by palladium-catalyzed decarboxylative allylation : total syntheses of (±)-centrolobine and (+)-decytospolides A and Ben_US
dc.typeJournal Article
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.identifier.doihttp://dx.doi.org/10.1002/chem.201303328


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record