dc.contributor.authorPeriyasamy, Vijitha
dc.contributor.authorPramanik, Manojit
dc.date.accessioned2014-04-29T01:21:20Z
dc.date.available2014-04-29T01:21:20Z
dc.date.copyright2014en_US
dc.date.issued2014
dc.identifier.citationPeriyasamy, V., & Pramanik, M. (2014). Monte Carlo simulation of light transport in turbid medium with embedded object—spherical, cylindrical, ellipsoidal, or cuboidal objects embedded within multilayered tissues. Journal of Biomedical Optics, 19(4), 045003-.en_US
dc.identifier.issn1083-3668en_US
dc.identifier.urihttp://hdl.handle.net/10220/19269
dc.description.abstractMonte Carlo modeling of light transport in multilayered tissue (MCML) is modified to incorporate objects of various shapes (sphere, ellipsoid, cylinder, or cuboid) with a refractive-index mismatched boundary. These geometries would be useful for modeling lymph nodes, tumors, blood vessels, capillaries, bones, the head, and other body parts. Mesh-based Monte Carlo (MMC) has also been used to compare the results from the MCML with embedded objects (MCML-EO). Our simulation assumes a realistic tissue model and can also handle the transmission/reflection at the object-tissue boundary due to the mismatch of the refractive index. Simulation of MCML-EO takes a few seconds, whereas MMC takes nearly an hour for the same geometry and optical properties. Contour plots of fluence distribution from MCML-EO and MMC correlate well. This study assists one to decide on the tool to use for modeling light propagation in biological tissue with objects of regular shapes embedded in it. For irregular inhomogeneity in the model (tissue), MMC has to be used. If the embedded objects (inhomogeneity) are of regular geometry (shapes), then MCML-EO is a better option, as simulations like Raman scattering, fluorescent imaging, and optical coherence tomography are currently possible only with MCML.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesJournal of biomedical opticsen_US
dc.rights© 2014 Society of Photo-Optical Instrumentation Engineers. This paper was published in Journal of Biomedical Optics and is made available as an electronic reprint (preprint) with permission of SPIE. The paper can be found at the following official DOI: [http://dx.doi.org/10.1117/1.JBO.19.4.045003].  One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.en_US
dc.subjectDRNTU::Science::Medicine::Biomedical engineering
dc.titleMonte Carlo simulation of light transport in turbid medium with embedded object : spherical, cylindrical, ellipsoidal, or cuboidal objects embedded within multilayered tissuesen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.identifier.doihttp://dx.doi.org/10.1117/1.JBO.19.4.045003
dc.description.versionPublished versionen_US
dc.identifier.rims178076


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