Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery
Yen, Swee Kuan
Selvan, Subramanian Tamil
Date of Issue2013
Lee Kong Chian School of Medicine
In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecule delivery such as micro ribonucleic acid (microRNA). This review intends to highlight the recent advances in the synthesis and application of multifunctional NPs (mainly iron oxide) in theranostics, an area used to combine therapeutics and diagnostics. The recent applications of NPs in miRNA delivery are also reviewed.
© 2013 Ivyspring International Publisher. This paper was published in Theranostics and is made available as an electronic reprint (preprint) with permission of Ivyspring International Publisher. The paper can be found at the following official DOI: [http://dx.doi.org/10.7150/thno.4827]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.