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|Title:||Amide synthesis by nucleophilic attack of vinyl azides||Authors:||Zhang, Feng-Lian
Lonca, Geoffroy Hervé
|Keywords:||DRNTU::Science::Chemistry::Inorganic chemistry::Synthesis||Issue Date:||2014||Source:||Zhang, F.-L., Wang, Y.-F., Lonca, G. H., Zhu, X., & Chiba, S. (2014). Amide Synthesis by Nucleophilic Attack of Vinyl Azides. Angewandte Chemie International Edition, 53(17), 4390-4394.||Series/Report no.:||Angewandte chemie international edition||Abstract:||A method for the synthesis of amide-containing molecules was developed using vinyl azides as an enamine-type nucleophile towards carbon electrophiles, such as imines, aldehydes, and carbocations that were generated from alcohols in the presence of BF3⋅OEt2. After nucleophilic attack of the vinyl azide, a substituent of the resulting iminodiazonium ion intermediate migrates to form a nitrilium ion, which is hydrolyzed to afford the corresponding amide.||URI:||https://hdl.handle.net/10356/97105
|ISSN:||1433-7851||DOI:||http://dx.doi.org/10.1002/anie.201400938||Rights:||© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.||Fulltext Permission:||none||Fulltext Availability:||No Fulltext|
|Appears in Collections:||SPMS Journal Articles|
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