Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering
Date of Issue2014
School of Electrical and Electronic Engineering
Phasoscopy is a recently proposed concept correlating electromagnetic (EM) absorption and scattering properties based on energy conservation. Phase information can be extracted from EM absorption induced acoustic wave and scattered EM wave for biological tissue characterization. In this paper, a novel imaging modality, termed photoacoustic phasoscopy (PAPS) imaging, is proposed and verified experimentally based on phasoscopy concept with laser illumination. Both endogeneous photoacoustic wave and scattered photons are collected simultaneously to extract the phase information, and phasoscopy image is then reconstructed by mapping phase distribution. The phasoscopy imaging experiments on vessel-mimicking phantom and ex vivo porcine tissues demonstrate significantly improved contrast than conventional photoacoustic imaging.
DRNTU::Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
© 2014 SPIE. This paper was published in Progress in Biomedical Optics and Imaging - Proceedings of SPIE and is made available as an electronic reprint (preprint) with permission of SPIE. The paper can be found at the following official DOI: [http://dx.doi.org/10.1117/12.2041867]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.