General suzuki coupling of heteroaryl bromides by using Tri-tert-butylphosphine as a supporting ligand
Zhou, Steve Jianrong
Date of Issue2014
School of Physical and Mathematical Sciences
A general procedure for the fast Suzuki coupling of major families of heteroaryl bromides was realized by using Pd(OAc)2/PtBu3 as the catalyst. Many couplings were finished within minutes at room temperature in n-butanol. Different from previous studies, three typical heteroaryl bromides were systematically examined in couplings of various heteroaryl and aryl boronic acids.
European journal of organic chemistry
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.