A synthesis of 5-hydroxysedamine using hydroformylation
Bates, Roderick W.
Aslam, Nur Filza Bte Mohamed
Tang, Chi H.
Date of Issue2014
School of Physical and Mathematical Sciences
A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hydroxy group.
DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
© 2014 Elsevier Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Tetrahedron, Elsevier Ltd. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [Article DOI: http://dx.doi.org/10.1016/j.tet.2014.02.001].