Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/103844
Title: Catalytic enantioselective alkylation of sulfenate anions to chiral heterocyclic sulfoxides using halogenated pentanidium salts
Authors: Zong, Lili
Ban, Xu
Kee, Choon Wee
Tan, Choon-Hong
Keywords: DRNTU::Science::Chemistry::Physical chemistry::Catalysis
Issue Date: 2014
Source: g, L., Ban, X., Kee, C. W., & Tan, C.-H. (2014). Catalytic enantioselective alkylation of sulfenate anions to chiral heterocyclic sulfoxides using halogenated pentanidium salts. Angewandte chemie international edition, 53(44), 11849-11853.
Series/Report no.: Angewandte chemie international edition
Abstract: We report halogenated pentanidiums as phase-transfer catalysts for the asymmetric alkylation of sulfenate anions to various sulfoxides with high enantioselectivities (up to 99 % ee) and yields (up to 99 %). This approach gives access to enantioenriched heterocyclic sulfoxides that might not be compatible with strong oxidants or organometallic reagents. Computational studies have revealed that the multiple noncovalent interactions such as halogen bonds and nonclassical hydrogen bonds are involved.
URI: https://hdl.handle.net/10356/103844
http://hdl.handle.net/10220/24638
ISSN: 1433-7851
DOI: 10.1002/anie.201407512
Rights: © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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