Gram-positive antimicrobial activity of amino acid-based hydrogels
Leow, Wan Ru
Tang, Mark B. Y.
Date of Issue2014
School of Materials Science and Engineering
Antimicrobial hydrogels are prepared based on the co-assembly of commercial Fmoc-phenylalanine and Fmoc-leucine, which act as the hydrogelator and antimicrobial building block, respectively. This co-assembled antimicrobial hydrogel is demonstrated to exhibit selective bactericidal activity for gram-positive bacteria while being biocompatible with normal mammalian cells, showing great potential as an antimicrobial coating for clinical anti-infective applications.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.