dc.contributor.authorMurukeshan, Vadakke M.
dc.contributor.authorLim, Hoong-Ta
dc.contributor.editorLuo, Qingming*
dc.contributor.editorLi, Xingde*
dc.contributor.editorGu, Ying*
dc.contributor.editorTang, Yuguo*
dc.identifier.citationMurukeshan, V. M., & Lim, H.-T. (2014). Hybrid-modality high-resolution Imaging : for diagnostic biomedical imaging and sensing for disease diagnosis. Proceedings of SPIE- Optics in Health Care and Biomedical Optics VI, 9268, 92680U-.en_US
dc.description.abstractMedical diagnostics in the recent past has seen the challenging trend to come up with dual and multi-modality imaging for implementing better diagnostic procedures. The changes in tissues in the early disease stages are often subtle and can occur beneath the tissue surface. In most of these cases, conventional types of medical imaging using optics may not be able to detect these changes easily due to its penetration depth of the orders of 1 mm. Each imaging modality has its own advantages and limitations, and the use of a single modality is not suitable for every diagnostic applications. Therefore the need for multi or hybrid-modality imaging arises. Combining more than one imaging modalities overcomes the limitation of individual imaging method and integrates the respective advantages into a single setting. In this context, this paper will be focusing on the research and development of two multi-modality imaging platforms. The first platform combines ultrasound and photoacoustic imaging for diagnostic applications in the eye. The second platform consists of optical hyperspectral and photoacoustic imaging for diagnostic applications in the colon. Photoacoustic imaging is used as one of the modalities in both platforms as it can offer deeper penetration depth compared to optical imaging. The optical engineering and research challenges in developing the dual/multi-modality platforms will be discussed, followed by initial results validating the proposed scheme. The proposed schemes offer high spatial and spectral resolution imaging and sensing, and is expected to offer potential biomedical imaging solutions in the near future.en_US
dc.format.extent9 p.en_US
dc.rights© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE). This paper was published in Proceedings of SPIE- Optics in Health Care and Biomedical Optics VI and is made available as an electronic reprint (preprint) with permission of Society of Photo-Optical Instrumentation Engineers (SPIE). The paper can be found at the following official DOI: [http://dx.doi.org/10.1117/12.2074654].  One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.en_US
dc.subjectDRNTU::Science::Medicine::Biomedical engineering
dc.titleHybrid-modality high-resolution Imaging: for diagnostic biomedical imaging and sensing for disease diagnosisen_US
dc.typeConference Paper
dc.contributor.conferenceOptics in Health Care and Biomedical Optics VIen_US
dc.contributor.researchCentre for Optical and Laser Engineeringen_US
dc.contributor.schoolSchool of Mechanical and Aerospace Engineeringen_US
dc.description.versionPublished versionen_US

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