Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
Murukeshan, Vadakke Matham
Date of Issue2014
School of Mechanical and Aerospace Engineering
Rolls-Royce@NTU Corporate Lab
This article reviews different waveguide based architectures forlabel-free detection of biomolecules. Working principles of various configurationsare discussed with an emphasis on their sensing principle and sensitivity. Later part of the article demonstrates a silicon waveguide Bragg grating resonator array as a highly sensitive refractive index sensor device for multiplexed detection of multi-analytes. Main features of the sensor element are discussed through numerical simulation, and proof-of concept device is demonstrated through micro fabrication. The proposed configuration of silicon waveguide based sensor array is expected to find potential application in portable chip based devices as highly sensitive multiplexed biosensors.
Journal of the Indian institute of science
© 2014 Indian Institute of Science. This paper was published in Journal of the Indian Institute of Science and is made available as an electronic reprint (preprint) with permission of Indian Institute of Science. The paper can be found at the following URL: [http://journal.iisc.ernet.in/index.php/iisc/article/view/4512]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.