High speed photoacoustic tomography system with low cost portable pulsed diode laser
Upputuri, Paul Kumar
Date of Issue2015
International Conference on Optical and Photonic Engineering (icOPEN 2015)
School of Chemical and Biomedical Engineering
Photoacoustic tomography (PAT) is a potential hybrid imaging modality that has attracted great attention in the fields of medical imaging. In order to generate photoacoustic signal efficiently Q-switched Nd:YAG pump lasers capable of generating tens of millijoules of nanosecond laser pulses have been widely used. However, PAT systems using such lasers have limitations in clinical applications because of their high cost, large size, and cooling requirements. Furthermore, the low pulse repetition rate (PRR) of tens of hertz is not suitable for real-time PAT. So, there is a need for inexpensive, compact, simple, fast imaging system for clinical applications. Nanosecond pulsed laser diodes could meet these requirements. In this work, we present a high-speed photoacoustic tomography imaging system that uses a compact and yet relatively powerful near-infrared pulsed laser diode. The PAT system was tested on phantoms to verify its potential imaging speed. Photoacoustic reconstructed images at different scanning speeds are presented. With single ultrasound detector scanning, the system could provide PA image ~10 times faster than the Nd:YAG laser based systems.
© 2015 [SPIE] This paper was published in [Proceedings SPIE 9524] and is made available as an electronic reprint (preprint) with permission of [SPIE]. The published version is available at: [http://dx.doi.org/10.1117/12.2186136]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.