A simple and non-contact optical imaging probe for evaluation of corneal diseases
Hong, Xun Jie Jeesmond
Shinoj, Vengalathunadakal K.
Murukeshan, Vadakke Matham
Date of Issue2015
School of Mechanical and Aerospace Engineering
Non-contact imaging techniques are preferred in ophthalmology. Corneal disease is one of the leading causes of blindness worldwide, and a possible way of detection is by analyzing the shape and optical quality of the cornea. Here, a simple and cost-effective, non-contact optical probe system is proposed and illustrated. The probe possesses high spatial resolutions and is non-dependent on coupling medium, which are significant for a clinician and patient friendly investigation. These parameters are crucial, when considering an imaging system for the objective diagnosis and management of corneal diseases. The imaging of the cornea is performed on ex vivo porcine samples and subsequently on small laboratory animals, in vivo. The clinical significance of the proposed study is validated by performing imaging of the New Zealand white rabbit’s cornea infected with Pseudomonas.
Review of Scientific Instruments
© 2015 AIP Publishing LLC. This paper was published in Review of Scientific Instruments and is made available as an electronic reprint (preprint) with permission of AIP Publishing. The published version is available at: [http://dx.doi.org/10.1063/1.4929684]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.