dc.contributor.authorWu, Junliang
dc.contributor.authorYoshikai, Naohiko
dc.date.accessioned2015-10-12T03:20:37Z
dc.date.available2015-10-12T03:20:37Z
dc.date.copyright2015en_US
dc.date.issued2015
dc.identifier.citationWu, J., & Yoshikai, N. (2015). Modular Synthesis of Multisubstituted Furans through Palladium-Catalyzed Three-Component Condensation of Alkynylbenziodoxoles, Carboxylic Acids, and Imines. Angewandte Chemie - International Edition, 54(38), 11107-11111.en_US
dc.identifier.issn1433-7851en_US
dc.identifier.urihttp://hdl.handle.net/10220/38788
dc.description.abstractMild and regiocontrolled synthesis of a multisubstituted furan is achieved through Pd(OAc)2-catalyzed room-temperature condensation of an alkynylbenziodoxole, a carboxylic acid, and an enolizable ketimine, which contribute to C1, CO, and C2 fragments, respectively, to the furan skeleton. The reaction tolerates a broad range of functional groups in each of the reaction components, and enables highly modular and flexible synthesis of variously substituted furans. The reaction is particularly effective for the rapid generation of tri- and tetraarylfurans and furan-containing oligoarylenes without relying on conventional cross-coupling chemistry.en_US
dc.description.sponsorshipNRF (Natl Research Foundation, S’pore)en_US
dc.format.extent5p.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesAngewandte Chemie - International Editionen_US
dc.rights© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the author created version of a work that has been peer reviewed and accepted for publication by Angewandte Chemie - International Edition, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1002/anie.201504687].en_US
dc.subjectDRNTU::Science::Chemistryen_US
dc.titleModular Synthesis of Multisubstituted Furans through Palladium-Catalyzed Three-Component Condensation of Alkynylbenziodoxoles, Carboxylic Acids, and Iminesen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.identifier.doihttp://dx.doi.org/10.1002/anie.201504687
dc.description.versionAccepted versionen_US


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