dc.contributor.authorDorajoo, Rajkumar
dc.contributor.authorLiu, Jianjun
dc.contributor.authorBoehm, Bernhard Otto
dc.date.accessioned2015-12-10T04:58:04Z
dc.date.available2015-12-10T04:58:04Z
dc.date.issued2015
dc.identifier.citationDorajoo, R., Liu, J., & Boehm, B. O. (2015). Genetics of Type 2 Diabetes and Clinical Utility. Genes, 6, 372-384.en_US
dc.identifier.issn2073-4425en_US
dc.identifier.urihttp://hdl.handle.net/10220/39027
dc.description.abstractA large proportion of heritability of type 2 diabetes (T2D) has been attributed to inherent genetics. Recent genetic studies, especially genome-wide association studies (GWAS), have identified a multitude of variants associated with T2D. It is thus reasonable to question if these findings may be utilized in a clinical setting. Here we briefly review the identification of risk loci for T2D and discuss recent efforts and propose future work to utilize these loci in clinical setting—for the identification of individuals who are at particularly high risks of developing T2D and for the stratification of specific health-care approaches for those who would benefit most from such interventions.en_US
dc.description.sponsorshipASTAR (Agency for Sci., Tech. and Research, S’pore)en_US
dc.format.extent13 p.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesGenesen_US
dc.rights© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.subjectType 2 diabetesen_US
dc.subjectGeneticsen_US
dc.subjectClinical utilityen_US
dc.titleGenetics of Type 2 Diabetes and Clinical Utilityen_US
dc.typeJournal Article
dc.contributor.schoolLee Kong Chian School of Medicine
dc.identifier.doihttp://dx.doi.org/10.3390/genes6020372
dc.description.versionPublished versionen_US


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