dc.contributor.authorUpputuri, Paul Kumar
dc.contributor.authorPramanik, Manojit
dc.identifier.citationUpputuri, P. K., & Pramanik, M. (2015). Pulsed laser diode based optoacoustic imaging of biological tissues. Biomedical Physics & Engineering Express, 1(4), 045010-.en_US
dc.description.abstractOptoacoustic tomography (OAT) is a promising hybrid imaging modality for many biomedical applications. However, the use of Nd:YAG laser as excitation source makes the OAT system expensive, and non-portable. Miniaturization of OAT system is an immediate task to make it a potential tool for both preclinical and clinical studies. In this work, we present an OA system that uses a miniaturized pulsed laser diode which can provide near infrared pulses at ~803 nm. With laser fluence ~0.3 mJ cm−2 on the tissue surface, we achieved 3 cm deep imaging in chicken tissue. The high pulse repetition rate of the diode laser allowed rapid acquisition of OA cross-sectional images with good image quality. The results promise that the proposed system has potential to be used as an alternative to Nd:YAG based OAT systems for biological imaging applications.en_US
dc.description.sponsorshipMOE (Min. of Education, S’pore)en_US
dc.format.extent9 p.en_US
dc.relation.ispartofseriesBiomedical Physics & Engineering Expressen_US
dc.rights© 2015 IOP Publishing Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Biomedical Physics & Engineering Express, IOP Publishing Ltd. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1088/2057-1976/1/4/045010].en_US
dc.subjectOptoacoustic tomographyen_US
dc.subjectPulsed laser diode
dc.subjectDeep tissue imaging
dc.subjectBiological imaging
dc.titlePulsed laser diode based optoacoustic imaging of biological tissuesen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.description.versionAccepted versionen_US

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