Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/81715
Title: | Fast photoacoustic-guided depth-resolved Raman spectroscopy: a feasibility study | Authors: | Gao, Fei Ong, Yi Hong Li, Gaoming Feng, Xiaohua Liu, Quan Zheng, Yuanjin |
Keywords: | Raman spectroscopy Depth-resolved |
Issue Date: | 2015 | Source: | Gao, F., Ong, Y. H., Li, G., Feng, X., Liu, Q., & Zheng, Y. (2015). Fast photoacoustic-guided depth-resolved Raman spectroscopy: a feasibility study. Optics Letters, 40(15), 3568-3571. | Series/Report no.: | Optics Letters | Abstract: | In this Letter, photoacoustic-guided Raman spectroscopy (PARS) is proposed for a fast depth-resolved Raman measurement with accurate depth localization. The approach was experimentally demonstrated to receive both photoacoustic and Raman signals from a three-layer agar phantom based on a developed synergic photoacoustic-Raman probe, showing strong depth correlation and achieving magnitude of faster operation speed due to photoacoustic time-of-flight measurement and guidance, compared with the conventional depth-resolved Raman spectroscopy method. In addition, further combination with advanced optical-focusing techniques in biological-scattering medium could potentially enable the proposed approach for cancer diagnostics with both tight and fast optical focusing at the desired depth of tumor. | URI: | https://hdl.handle.net/10356/81715 http://hdl.handle.net/10220/39610 |
ISSN: | 0146-9592 | DOI: | 10.1364/OL.40.003568 | Schools: | School of Chemical and Biomedical Engineering School of Electrical and Electronic Engineering |
Rights: | © 2015 Optical Society of America. This paper was published in Optics Letters and is made available as an electronic reprint (preprint) with permission of Optical Society of America. The published version is available at: [http://dx.doi.org/10.1364/OL.40.003568]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | EEE Journal Articles SCBE Journal Articles |
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PA-guided Raman spectroscopy rev.pdf | 301.85 kB | Adobe PDF | View/Open |
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