Polysubstituted pyrrole derivatives via 1,2-alkenyl migration of novel γ-amino-α,β-unsaturated aldehydes and α-diazocarbonyls
Date of Issue2014
School of Physical and Mathematical Sciences
Tri-substituted pyrrole derivatives were successfully synthesized from aminoaldehyde and α-diazocarbonyl, using a TiCl4 catalyst. The reactions proceeded via 1,2-migration and condensation, leading to the corresponding pyrroles in moderate to excellent yields. Reaction susceptibility was subsequently demonstrated by the variation in substrates.
Physical and Mathematical Sciences
© 2014 The Royal Society of Chemistry. This is the author created version of a work that has been peer reviewed and accepted for publication by RSC Advances, The Royal Society of Chemistry. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1039/c3ra47020b].