Nickel-catalyzed asymmetric transfer hydrogenation of conjugated olefins
Zhou, Jianrong Steve
Date of Issue2015-06-12
School of Physical and Mathematical Sciences
Asymmetric transfer hydrogenation of electron-deficient olefins is realized with nickel catalysts supported by strongly σ-donating bisphosphines. Deuterium labeling experiments point to a reaction sequence of formate decarboxylation, asymmetric hydride insertion and non-stereoselective protonation of resulting nickel enolates.
Chemistry and Biological Chemistry
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