A concise route to the highly-functionalized azetidine precursor: the enantioselective synthesis of penaresidin B
Kock, Si Min
Leow, Min Li
Date of Issue2015
School of Physical and Mathematical Sciences
An efficient and high-yielding synthesis of penaresidin B is disclosed herein. The concise 8-step synthesis of azetidine aldehyde was devised by incorporating our novel strategy for ready access to 3-amino-2,3-dideoxysugars via regio- and stereoselective tandem hydroamination/glycosylation of glycal as the key step.
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.