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      Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties

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      Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties.pdf (2.006Mb)
      Author
      Ghadban, Ali
      Ahmed, Anansa S.
      Ping, Yuan
      Ramos, Ricardo
      Arfin, Najmul
      Cantaert, Bram
      Ramanujan, Raju Vijayaraghavan
      Miserez, Ali
      Date of Issue
      2015-10-30
      School
      School of Materials Science and Engineering
      School of Biological Sciences
      Research Centre
      Centre for Biomimetic Sensor Science
      Version
      Published version
      Abstract
      We have developed pH- and magnetic-responsive hydrogels that are stabilized by both covalent bonding and catechol/Fe3+ ligands. The viscoelastic properties of the gels are regulated by the complexation valence and can be used to tune drug release profiles. The stable incorporation of magnetic nanoparticles further expands control over the mechanical response and drug release, in addition to providing magnetic stimuli-responsivity to the gels.
      Subject
      Drug release
      Type
      Journal Article
      Series/Journal Title
      Chemical Communications
      Rights
      This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
      Collections
      • MSE Journal Articles
      • SBS Journal Articles
      http://dx.doi.org/10.1039/C5CC08617E
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