Please use this identifier to cite or link to this item:
Title: Palladium-Catalyzed Heteroarylation and Concomitant ortho-Alkylation of Aryl Iodides
Authors: Lei, Chuanhu
Jin, Xiaojia
Zhou, Jianrong (Steve)
Keywords: cross-coupling
C-H activation
synthetic method
Issue Date: 2015
Source: Lei, C., Jin, X., & Zhou, J. (2015). Palladium-Catalyzed Heteroarylation and Concomitant ortho-Alkylation of Aryl Iodides. Angewandte Chemie International Edition, 54(45), 13397-13400.
Series/Report no.: Angewandte Chemie International Edition
Abstract: Three-component couplings were achieved from common aryl halides, alkyl halides, and heteroarenes under palladium and norbornene co-catalysis. The reaction forges hindered aryl–heteroaryl bonds and introduces ortho-alkyl groups to aryl rings. Various heterocycles such as oxazoles, thiazoles and thiophenes underwent efficient coupling. The heteroarenes were deprotonated in situ by bases without the assistance of palladium catalysts.
ISSN: 1433-7851
Rights: © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

Google ScholarTM



Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.