Formal Intermolecular Hydroamination of Unbiased Olefins for Primary Amine Formation
Wong, Nurul Imma
Date of Issue2015
School of Materials Science and Engineering
A Pd/Ir dual metal tandem catalyst system was found to be active in catalyzing the one-pot, two-step formal hydroamination of unbiased olefins such as 1-dodecene with an ammonia source to give branched primary amines in high yields of >85 % by using only 1 mol-% of the Ir catalyst. This is the first report of the formal one-pot intermolecular hydroamination of olefins to obtain primary amines.
European Journal of Organic Chemistry
© 2015 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the author created version of a work that has been peer reviewed and accepted for publication by European Journal of Organic Chemistry, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1002/ejoc.201403654].