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|Title:||Membrane feeding of dengue patient’s blood as a substitute for direct skin feeding in studying Aedes-dengue virus interaction||Authors:||Tan, Cheong-Huat
Wong, Pei-Sze Jeslyn
Li, Mei-Zhi Irene
Lee, Linda K.
Lye, David C.
Membrane Feeding Assay (MFA)
Direct Skin Feeding Assay (DFSA)
|Issue Date:||2016||Source:||Tan, C. H., Wong, P. S. J., Li, M. Z. I., Yang, H. T., Chong, C. S., Lee, L. K., et al. (2016). Membrane feeding of dengue patient’s blood as a substitute for direct skin feeding in studying Aedes-dengue virus interaction. Parasites & Vectors, 9, 211-.||Series/Report no.:||Parasites & Vectors||Abstract:||Background: Understanding the interaction between Aedes vectors and dengue viruses (DENV) has significant implications in determining the transmission dynamics of dengue. The absence of an animal model and ethical concerns regarding direct feeding of mosquitoes on patients has resulted in most infection studies using blood meals spiked with laboratory-cultured DENV. Data obtained from such studies may not reflect the natural human-mosquito transmission scenario. This study explored the potential of using membrane feeding of dengue patient’s blood as a substitute for direct skin feeding.||URI:||https://hdl.handle.net/10356/81506
|ISSN:||1756-3305||DOI:||http://dx.doi.org/10.1186/s13071-016-1469-6||Rights:||© 2016 Tan et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.||Fulltext Permission:||open||Fulltext Availability:||With Fulltext|
|Appears in Collections:||SBS Journal Articles|
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