dc.contributor.authorTan, Cheong-Huat
dc.contributor.authorWong, Pei-Sze Jeslyn
dc.contributor.authorLi, Mei-Zhi Irene
dc.contributor.authorYang, Hui-Ting
dc.contributor.authorChong, Chee-Seng
dc.contributor.authorLee, Linda K.
dc.contributor.authorYuan, Shi
dc.contributor.authorLeo, Yee-Sin
dc.contributor.authorNg, Lee-Ching
dc.contributor.authorLye, David C.
dc.date.accessioned2016-06-27T08:51:16Z
dc.date.available2016-06-27T08:51:16Z
dc.date.issued2016
dc.identifier.citationTan, C. H., Wong, P. S. J., Li, M. Z. I., Yang, H. T., Chong, C. S., Lee, L. K., et al. (2016). Membrane feeding of dengue patient’s blood as a substitute for direct skin feeding in studying Aedes-dengue virus interaction. Parasites & Vectors, 9, 211-.en_US
dc.identifier.issn1756-3305en_US
dc.identifier.urihttp://hdl.handle.net/10220/40807
dc.description.abstractBackground: Understanding the interaction between Aedes vectors and dengue viruses (DENV) has significant implications in determining the transmission dynamics of dengue. The absence of an animal model and ethical concerns regarding direct feeding of mosquitoes on patients has resulted in most infection studies using blood meals spiked with laboratory-cultured DENV. Data obtained from such studies may not reflect the natural human-mosquito transmission scenario. This study explored the potential of using membrane feeding of dengue patient’s blood as a substitute for direct skin feeding.en_US
dc.description.sponsorshipNMRC (Natl Medical Research Council, S’pore)en_US
dc.format.extent11 p.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesParasites & Vectorsen_US
dc.rights© 2016 Tan et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en_US
dc.subjectDengueen_US
dc.subjectAedes aegyptien_US
dc.subjectDirect Skin Feeding Assay (DFSA)en_US
dc.subjectMembrane Feeding Assay (MFA)en_US
dc.subjectEDTA blooden_US
dc.titleMembrane feeding of dengue patient’s blood as a substitute for direct skin feeding in studying Aedes-dengue virus interactionen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.identifier.doihttp://dx.doi.org/10.1186/s13071-016-1469-6
dc.description.versionPublished versionen_US


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