dc.contributor.authorCho, Nam-Joon
dc.contributor.authorLee, Choongho
dc.contributor.authorPang, Phillip S.
dc.contributor.authorPham, Edward A.
dc.contributor.authorFram, Benjamin
dc.contributor.authorNguyen, Khanh
dc.contributor.authorXiong, Anming
dc.contributor.authorSklan, Ella H.
dc.contributor.authorElazar, Menashe
dc.contributor.authorKoytak, Elif S.
dc.contributor.authorKersten, Caroline
dc.contributor.authorKanazawa, Kay K.
dc.contributor.authorFrank, Curtis W.
dc.contributor.authorGlenn, Jeffrey S.
dc.date.accessioned2016-09-19T08:21:14Z
dc.date.available2016-09-19T08:21:14Z
dc.date.issued2015
dc.identifier.citationCho, N. J., Lee, C., Pang, P. S., Pham, E. A., Fram, B., Nguyen, K., Xiong, A., Sklan, E. H., Elazar, M., Koytak, E. S., Kersten, C., Kanazawa, K. K., Frank, C. W., & Glenn, J. S. (2015). Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome. Gastroenterology, 148(3), 616-625.en_US
dc.identifier.issn00165085en_US
dc.identifier.urihttp://hdl.handle.net/10220/41454
dc.description.abstractPhosphoinositides (PIs) bind and regulate localization of proteins via a variety of structural motifs. PI 4,5-bisphosphate (PI[4,5]P2) interacts with and modulates the function of several proteins involved in intracellular vesicular membrane trafficking. We investigated interactions between PI(4,5)P2 and hepatitis C virus (HCV) nonstructural protein 5A (NS5A) and effects on the viral life cycle.en_US
dc.description.sponsorshipNMRC (Natl Medical Research Council, S’pore)en_US
dc.language.isoenen_US
dc.relation.ispartofseriesGastroenterologyen_US
dc.subjectQCMen_US
dc.subjectAntiviral Strategiesen_US
dc.subjectSignaling Moleculeen_US
dc.titlePhosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genomeen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Materials Science and Engineeringen_US
dc.identifier.doihttp://dx.doi.org/10.1053/j.gastro.2014.11.043


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record