Activatable Photoacoustic Nanoprobes for In Vivo Ratiometric Imaging of Peroxynitrite
Paul Kumar Upputuri
Date of Issue2016
School of Chemical and Biomedical Engineering
Organic semiconducting nanoprobes doped with bulky borane can undergo specific activation by ONOO− even at tumor-relevant acidic pH (6.8), permitting in vivo ratiometric photoacoustic imaging of ONOO− in the tumor environment of living mice.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the author created version of a work that has been peer reviewed and accepted for publication by Advanced Materials, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1002/adma.201604764].