dc.contributor.authorO’Rorke, Richard D.
dc.contributor.authorPokholenko, Oleksandr
dc.contributor.authorGao, Feng
dc.contributor.authorCheng, Ting
dc.contributor.authorShah, Ankur
dc.contributor.authorMogal, Vishal
dc.contributor.authorSteele, Terry W. J.
dc.date.accessioned2017-03-16T02:34:36Z
dc.date.available2017-03-16T02:34:36Z
dc.date.issued2017
dc.identifier.citationO’Rorke, R. D., Pokholenko, O., Gao, F., Cheng, T., Shah, A., Mogal, V., et al. (2017). Addressing Unmet Clinical Needs with UV Bioadhesives. Biomacromolecules, 18(3), 674-682.en_US
dc.identifier.issn1525-7797en_US
dc.identifier.urihttp://hdl.handle.net/10220/42167
dc.description.abstractThe invasive practice of suturing for wound closure has persisted for millennia; with the rate of medical development, it is staggering that there are few viable alternatives to invasive mechanical fasteners. Biocompatible and biodegradable polymers are attractive candidates for versatile bioadhesives and could revolutionize surgical procedures. Bioadhesives can be broadly placed into two groups: activated and instant. Almost all commercially available bioadhesives are instant, which cross-link by mixing two components or on contact with moisture. Activated bioadhesives, on the other hand, allow control of when and where a bioadhesive cross-links and, in some cases, the extent of cross-linking. Despite significant progress, there has been little translation of activated bioadhesives to clinical use. This review discusses recent developments in UV-activated bioadhesives toward addressing unmet clinical needs.en_US
dc.description.sponsorshipMOE (Min. of Education, S’pore)en_US
dc.format.extent9 p.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesBiomacromoleculesen_US
dc.rightsThis is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License, which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.en_US
dc.subjectUV-activated bioadhesivesen_US
dc.subjectUnmet clinical applicationsen_US
dc.titleAddressing Unmet Clinical Needs with UV Bioadhesivesen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Materials Science and Engineeringen_US
dc.identifier.doihttp://dx.doi.org/10.1021/acs.biomac.6b01743
dc.description.versionPublished versionen_US


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