Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection
Mac Aogáin, Micheál
Chotirmall, Sanjay Haresh
Rogers, Thomas R.
Smith, Stephen G. J.
Date of Issue2016
Lee Kong Chian School of Medicine
Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant E. coli of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage. Conclusion: This is the first report of a novel E. coli ST, ST-458, which caused pyelonephritis and bacteraemia.
Escherichia coli ST-458
JMM Case Reports
© 2016 The Authors (published by Microbiology Society). This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).