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https://hdl.handle.net/10356/83026
Title: | Advances in Neutrophil Testing In Type 2 Diabetes Mellitus | Authors: | Tay, Hui Min Hou, Han Wei Dalan, Rinkoo Boehm, Bernhard Otto |
Keywords: | Neutrophils Diabetes |
Issue Date: | 2017 | Source: | Hou, H. W., Tay, H. M., Dalan, R., & Boehm, B. O. (2017). Advances in Neutrophil Testing In Type 2 Diabetes Mellitus. Current Research in Diabetes & Obesity Journal, 1(5), 555572-. | Series/Report no.: | Current Research in Diabetes & Obesity Journal | Abstract: | Patients with type 2 diabetes mellitus (T2DM) suffer from impaired glucose metabolism which results in low-grade inflammation and activation of the innate immune system. Neutrophils the key effector cells of the innate immune system and heavily implicated in the pathogenesis of T2DM, are promising cell-based inflammatory biomarkers for immune health profiling, provided that they can be rapidly purified and measured with sufficient precision. In this review, we highlight recent advances in neutrophil isolation and functional assay using microfluidics technologies and the potential of their functional phenotype as a novel biomarker of vascular risk in diabetes. | URI: | https://hdl.handle.net/10356/83026 http://hdl.handle.net/10220/42383 |
URL: | https://juniperpublishers.com/crdoj/pdf/CRDOJ.MS.ID.555572.pdf | ISSN: | 2476-1435 | Schools: | Lee Kong Chian School of Medicine (LKCMedicine) | Rights: | This work is licensed under Creative Commons Attribution 4.0 License | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | LKCMedicine Journal Articles |
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CRDOJ.MS.ID.555572.pdf | 554.45 kB | Adobe PDF | View/Open |
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