Variations of bubble cavitation and temperature elevation during acculysis
Gao, Wilson Xiaobin
Date of Issue2017
AIP Conference Proceedings
School of Mechanical and Aerospace Engineering
High-intensity focused ultrasound (HIFU) is effective in both thermal ablations and soft-tissue fragmentation. Mechanical and thermal effects depend on the operating parameters and vary with the progress of therapy. Different types of lesions could be produced with the pulse duration of 5-30 ms, much longer than histotripsy burst but shorter than the time for tissue boiling, and pulse repetition frequency (PRF) of 0.2-5 Hz. Meanwhile, bubble cavitation and temperature elevation in the focal region were measured by passive cavitation detection (PCD) and thermocouples, respectively. Temperature in the pre-focal region is always higher than those at the focal and post-focal position in all tests. Overall, it is suggested that appropriate synergy and monitoring of mechanical and thermal effects would broaden the HIFU application and enhance its efficiency as well as safety.
© 2017 American Institute of Physics (AIP). This paper was published in AIP Conference Proceedings and is made available as an electronic reprint (preprint) with permission of American Institute of Physics (AIP). The published version is available at: [http://dx.doi.org/10.1063/1.4976615]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.