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Title: Contrast enhancement of spectral domain optical coherence tomography using spectrum correction
Authors: Ni, Guangming
Liu, Linbo
Yu, Xiaojun
Ge, Xin
Chen, Si
Liu, Xinyu
Wang, Xianghong
Chen, Shi
Keywords: Optical Coherence Tomography
Issue Date: 2017
Source: Ni, G., Liu, L., Yu, X., Ge, X., Chen, S., Liu, X., et al. (2017). Contrast enhancement of spectral domain optical coherence tomography using spectrum correction. Computers in Biology and Medicine, 89, 505-511.
Series/Report no.: Computers in Biology and Medicine
Abstract: We report a spectrum correction method to enhance the image contrast of spectral domain optical coherence tomography (SD-OCT). Our method treats SD-OCT signals as the product of harmonic signals backscattered from a sample comprising a series of discrete reflectors and a window corresponding to the light source spectrum. The method restores the magnitude of the main lobe of the axial point spread function (PSF) by estimating the magnitudes of the backscattered harmonic signals and strengthens OCT signals using these estimated values. Experimental results acquired from fresh rat corneas and fixed human aortic atherosclerosis tissues show that our method provides clearer microstructural information than the conventional methods by improving the contrast to noise ratios (CNRs) by 1.4779 dB and 3.2595 dB, respectively. This improved image quality is obtained without any hardware change, making our method a cost-effective alternative to compete with hardware advances.
ISSN: 0010-4825
Rights: © 2017 Elsevier. This is the author created version of a work that has been peer reviewed and accepted for publication by Computers in Biology and Medicine, Elsevier. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
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