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Title: Our Gut Microbiome: The Evolving Inner Self
Authors: Kundu, Parag
Blacher, Eran
Elinav, Eran
Pettersson, Sven
Keywords: Microbiome
Issue Date: 2017
Source: Kundu, P., Blacher, E., Elinav, E., & Pettersson, S. (2017). Our Gut Microbiome: The Evolving Inner Self. Cell, 171(7), 1481-1493.
Series/Report no.: Cell
Abstract: The “holobiont” concept, defined as the collective contribution of the eukaryotic and prokaryotic counterparts to the multicellular organism, introduces a complex definition of individuality enabling a new comprehensive view of human evolution and personalized characteristics. Here, we provide snapshots of the evolving microbial-host associations and relations during distinct milestones across the lifespan of a human being. We discuss the current knowledge of biological symbiosis between the microbiome and its host and portray the challenges in understanding these interactions and their potential effects on human physiology, including microbiome-nervous system inter-relationship and its relevance to human variation and individuality.
ISSN: 0092-8674
Rights: © 2017 Elsevier Inc. This is the author created version of a work that has been peer reviewed and accepted for publication by Cell, Elsevier Inc. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles
SCELSE Journal Articles

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