Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion
Sing, Swee Leong
Wiria, Florencia Edith
Ha, Thi Mai Hoa
Yeong, Wai Yee
Date of Issue2017
School of Mechanical and Aerospace Engineering
Singapore Centre for 3D Printing
Tissue engineering approaches have been adopted to address challenges in osteochondral tissue regeneration. Single phase scaffolds, which consist of only one single material throughout the whole structure, have been used extensively in these tissue engineering approaches. However, a single phase scaffold is insufficient in providing all the properties required for regeneration and repair of osteochondral defects. Biphasic scaffolds with two distinct phases of titanium/type 1 collagen and titanium-tantalum/type 1 collagen were developed for the first time using selective laser melting. Observation of the biphasic scaffolds demonstrated continuous interface between the two phases and mechanical characterization of the metallic scaffolds support the feasibility of the newly developed scaffolds for tissue engineering in osteochondral defects.
Selective Laser Melting
International Journal of Bioprinting
© 2017 Swee Leong Sing, et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.