Bioprinting in cardiovascular tissue engineering: a review
Lee, Jia Min
Sing, Swee Leong
Tan, Edgar Yong Sheng
Yeong, Wai Yee
Date of Issue2016
School of Mechanical and Aerospace Engineering
Singapore Centre for 3D Printing
Fabrication techniques for cardiac tissue engineering have been evolving around scaffold-based and scaffold-free approaches. Conventional fabrication approaches lack control over scalability and homogeneous cell distribution. Bioprinting provides a technological platform for controlled deposition of biomaterials, cells, and biological factors in an organized fashion. Bioprinting is capable of alternating heterogeneous cell printing, printing anatomical relevant structure and microchannels resembling vasculature network. These are essential features of an engineered cardiac tissue. Bioprinting can potentially build engineered cardiac construct that resembles native tissue across macro to nanoscale.
International Journal of Bioprinting
© 2016 Jia Min Lee, et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.