A challenging Heck reaction of maleimides
Lim, Li Hui
Zhou, Jianrong (Steve)
Date of Issue2015
School of Physical and Mathematical Sciences
Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent.
Organic Chemistry Frontiers
© 2015 the Partner Organisations. This is the author created version of a work that has been peer reviewed and accepted for publication by Organic Chemistry Frontiers, the Partner Organisations. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1039/C5QO00015G].