Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways
Leung, Hui Min
Ford, Timothy N.
Birket, Susan E.
Solomon, George M.
Rowe, Steven M.
Tearney, Guillermo J.
Date of Issue2017
Proceeding of SPIE 10056, Design and Quality for Biomedical Technologies X
School of Electrical and Electronic Engineering
Centre for OptoElectronics and Biophotonics
High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging technology to image several relevant respiratory epithelial functional microanatomy at 40 fps and at lateral and axial resolutions of 2 and 1.3μm, respectively. We now present the development of a portable μOCT imaging system with comparable optical and imaging performance, which enables the μOCT technology to be translated to the clinic for in vivo imaging of human airways.
© 2017 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Proceeding of SPIE 10056, Design and Quality for Biomedical Technologies X and is made available as an electronic reprint (preprint) with permission of SPIE. The published version is available at: [http://dx.doi.org/10.1117/12.2253423]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.