View Item 
      •   Home
      • 2. Research Centres and Institutes
      • Singapore Centre for Environmental Life Sciences and Engineering (SCELSE)
      • SCELSE Journal Articles
      • View Item
      •   Home
      • 2. Research Centres and Institutes
      • Singapore Centre for Environmental Life Sciences and Engineering (SCELSE)
      • SCELSE Journal Articles
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.
      Subject Lookup

      Browse

      All of DR-NTUCommunities & CollectionsTitlesAuthorsBy DateSubjectsThis CollectionTitlesAuthorsBy DateSubjects

      My Account

      Login

      Statistics

      Most Popular ItemsStatistics by Country/RegionMost Popular Authors

      About DR-NTU

      Separation of pathogenic bacteria by chain length

      Thumbnail
      Separation of pathogenic bacteria by chain length.pdf (3.546Mb)
      Author
      Beech, Jason P.
      Ho, Bao Dang
      Garriss, Geneviève
      Oliveira, Vitor
      Henriques-Normark, Birgitta
      Tegenfeldt, Jonas O.
      Date of Issue
      2018
      School
      Lee Kong Chian School of Medicine (LKCMedicine)
      Related Organization
      Singapore Centre for Environmental Life Sciences Engineering
      Version
      Published version
      Abstract
      Using Deterministic Lateral Displacement devices optimized for sensitivity to particle length, we separatesubpopulations of bacteria depending on known properties that affect their capability to cau se disease(virulence). For the human bacterial pathogen Streptococcus pneumoniae, bacterial chain length and the presence of a capsule are known virulence factors contributing to its ability to cause severe disease.Separation of cultured pneumococci into subpopulations based on morphological type (single cocci,diplococci and chains) will enable more detailed studies of the role they play in virulence. Moreover, wepresent separation of mixed populations of almost genetically identical encapsulated and non-encapsulated pneumococcal strains in our device.
      Subject
      Deterministic Lateral Displacement
      Separation
      Type
      Journal Article
      Series/Journal Title
      Analytica Chimica Acta
      Rights
      © 2017 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
      Collections
      • SCELSE Journal Articles
      • LKCMedicine Journal Articles
      http://dx.doi.org/10.1016/j.aca.2017.11.050
      Get published version (via Digital Object Identifier)

      Show full item record


      NTU Library, Nanyang Avenue, Singapore 639798 © 2011 Nanyang Technological University. All rights reserved.
      DSpace software copyright © 2002-2015  DuraSpace
      Contact Us | Send Feedback
      Share |    
      Theme by 
      Atmire NV
       

       


      NTU Library, Nanyang Avenue, Singapore 639798 © 2011 Nanyang Technological University. All rights reserved.
      DSpace software copyright © 2002-2015  DuraSpace
      Contact Us | Send Feedback
      Share |    
      Theme by 
      Atmire NV
       

       

      DCSIMG