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|Title:||Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy||Authors:||Limviphuvadh, Vachiranee
Tan, Chee Seng
Xiang, Joy Shengnan
Mu, Yar Soe
Soo, Ross A.
Yong, Wei Peng
Chin, Lee Soo
|Issue Date:||2018||Source:||Limviphuvadh, V., Tan, C. S., Konishi, F., Jenjaroenpun, P., Xiang, J. S., Kremenska, Y., et al. (2018). Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy. BMC Cancer, 18(1), 555-.||Series/Report no.:||BMC Cancer||Abstract:||Single Nucleotide Polymorphisms (SNPs) can influence patient outcome such as drug response and toxicity after drug intervention. The purpose of this study is to develop a systematic pathway approach to accurately and efficiently predict novel non-synonymous SNPs (nsSNPs) that could be causative to gemcitabine-based chemotherapy treatment outcome in Singaporean non-small cell lung cancer (NSCLC) patients.||URI:||https://hdl.handle.net/10356/84498
|ISSN:||1471-2407||DOI:||10.1186/s12885-018-4471-x||Rights:||© The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.||Fulltext Permission:||open||Fulltext Availability:||With Fulltext|
|Appears in Collections:||SCSE Journal Articles|
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