Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/86306
Title: Viral and antibody kinetics, and mosquito infectivity of an imported case of Zika fever due to Asian genotype (American strain) in Singapore
Authors: Tan, Cheong Huat
Tan, Li Kiang
Hapuarachchi, Hapuarachchige Chanditha
Lai, Yee Ling
Wong, Pei Sze Jeslyn
Mak, Keng Wai
Yap, Grace
Wong, Wing Yan
Leo, Yee Sin
Wong, Mei Chun
Ng, Lee Ching
Keywords: Zika Virus
Antibody
Issue Date: 2018
Source: Tan, C. H., Tan, L. K., Hapuarachchi, H. C., Lai, Y. L., Wong, P. S. J., Yap, G., et al. (2018). Viral and antibody kinetics, and mosquito infectivity of an imported case of Zika fever due to Asian genotype (American strain) in Singapore. Viruses, 10(1), 44-.
Series/Report no.: Viruses
Abstract: We report a case of a Singaporean who acquired Zika virus (ZIKV) during a visit to Cuba. The infection was confirmed using molecular and serological methods. This report highlights potential drawbacks of using IgG serology for diagnosis of flavivirus infections in endemic regions. The low viremia detected during the early phase of this case resulted in low mosquito infectivity rates, suggesting the possibility of ZIKV transmission prior to clinical onset. The report also emphasizes the challenges of public health interventions for Zika fever and the importance of sustaining a low vector population to reduce the risk of arbovirus transmission in vulnerable regions.
We report a case of a Singaporean who acquired Zika virus (ZIKV) during a visit to Cuba. The infection was confirmed using molecular and serological methods. This report highlights potential drawbacks of using IgG serology for diagnosis of flavivirus infections in endemic regions. The low viremia detected during the early phase of this case resulted in low mosquito infectivity rates, suggesting the possibility of ZIKV transmission prior to clinical onset. The report also emphasizes the challenges of public health interventions for Zika fever and the importance of sustaining a low vector population to reduce the risk of arbovirus transmission in vulnerable regions.
URI: https://hdl.handle.net/10356/86306
http://hdl.handle.net/10220/45231
ISSN: 1999-4915
DOI: http://dx.doi.org/10.3390/v10010044
Rights: © 2018 by The Author(s). Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SBS Journal Articles

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